Dalian blue sky Pa fire. 20 kg of liquor into the belly, toothpaste and blade can present food and wine. From the Spring Festival draws near, the frequency might be wet bar higher and higher into the sky tyrants who do not drink that. But if you are a non-drinking is not, how do you make yourself less bitter by the point of it?
Choose the cup is a science
If some choose, remember to choose thin high cup, can choose a small cup outsole mouth better. Since the volume of a cylinder formula is V = r 2 h, in order to keep the volume constant, every narrow radius n times, n 2 times the height must be increased. A small cup of reduced radius in the visual effect is not obvious, but very significant increase in height, it makes people feel more tall, thin glass, so you can unknowingly drink some wine. Plus special people usually will not fall over in the pouring time, if it is smaller than the bottom of the cup cup cup, can hold receptions in fact less, because the liquid level and it looks the same and appears as an ordinary cup many.
After selecting the cup, in respect of the wine selection
In the body responsible attitude, of course, the lower the alcohol content, the better. But usually Pinjiu holidays, this is unlikely to happen. So, tadpole Jun crooked trick is: the election is not so fragrant wine. If the wine is not so tasty, would have been drinking less. In addition, the wine aromas of the wine "homologue" (congeners) result. Homologs wine during fermentation alcohol formed in addition to the "effective impurity." They are suspended in an alcohol solution after distillation, the distilled spirits can give additional flavor, color and aroma and the like. Our spirits were mostly distilled liquor. Research found that wine homologues make hangover worse. Flavor is not strong wine legend homologues less than the body can metabolize alcohol less more additional burden.
This finally began to drink, the most important thing is do not worry
Eat first before drinking
Gastric mucosal barrier membrane of epithelial cells in the stomach near the side of the stomach cavity closely connected to form, blocking the stomach cavity of gastric mucosal violations within the organization. High concentrations of alcohol can directly damage the gastric mucosal barrier, coupled with acid corrosion, eventually leading to gastric erosion and bleeding. So before drinking, be sure to have something to eat.
Meat and other fatty foods do not digest, except to protect the gastric mucosa, but also can reduce the penetration of alcohol absorption. Protein foods rich in amino acids, can accelerate the decomposition of alcohol metabolism. But do not use salted fish, sausage, bacon and other cured products, drinks, and more of these products contain nitrosamines, nitrosamines greater solubility in alcohol, can increase the risk of esophageal cancer, the risk of gastric cancer.
Drinking wine can drink non-carbonated drinks
The same rate of drinking, drink non-alcoholic beverages blending wine is equivalent to reducing the over-concentration of alcohol, can slow down the absorption of alcohol. However, legendary with honey or fruit juice (fructose) to hangover method was not very reliable. An equal volume of beverages and wine, sugar, much less than the alcohol content, and in related research, taking to 10 ml of alcohol while taking 31 grams of fructose to achieve the hangover effect [1].
Do not drink carbonated beverages because the carbon dioxide gas in the beverage can stomach the rapid expansion of the area of the stomach to increase the absorption of alcohol, but also to promote the speed of alcohol into the small intestine, increase the absorption of alcohol in the small intestine.
Eat something and drink before a truth, but also the way to drink a small mouth slowly drink, eat and drink, to dilute the concentration of alcohol, slow alcohol into the blood of the time.
Drink the wine began metabolized
Alcohol is metabolized primarily by the liver. Absorbed into the bloodstream through the stomach and small intestine ethanol, enter the liver through the portal vein, 90% alcohol by alcohol dehydrogenase (ADH) into acetaldehyde, then 2 (ALDH2) converted to acetic acid by acetaldehyde dehydrogenases, then converted to heat (final product is water and carbon dioxide) or stored as fat. Left about 10 percent of the alcohol in the prototype through urine, sweat and breath excreted.
The whole process requires a lot of water, therefore, whether it is when drinking or drunk, drinking lots of water can help the body more quickly alcohol excreted.
A lot of people would blush when alcohol metabolism, tadpoles Jun advise, so best not to drink. Drinking blush culprit is acetaldehyde. Acetaldehyde many tissues and organs are toxic, can cause DNA damage, and are thought to have carcinogenic effects. In animal studies with acetaldehyde to do even mutagen cancer model. ALDH2 if a problem, it is easy to large accumulation of acetaldehyde, and soon you will blush. It is easy drinking blush acetaldehyde metabolism of flawed people, and in the gene, it is not to drink non-drinking also ALDH2 Lys / Glu heterozygote. Normal people have normal ALDH2, faster metabolism of acetaldehyde, is not likely to cause the accumulation of acetaldehyde, slightly smaller health hazards. But for genetic defects in people, is divided into two cases. ALDH2 Lys / Lys homozygote, total incapacity to metabolize alcohol, numerous liquor, soon drunk, but not to drink it, it will not have any major impact on health. But if ALDH2 Lys / Glu heterozygous ALDH2 due or have weak activity through constant temper, will gradually acetaldehyde, blush phenomenon tolerance, become habitual heavy drinkers. Although not drunk, but in fact the accumulation of acetaldehyde in the body, more and more damage to the body increases.
Studies have shown that people who for alcoholism, ALDH2 Lys487 allele at the same time high has an important influence on the blush and esophageal cancer, the risk can only ALDH2 Lys / Glu heterozygote If the person alcohol, it may suffer from esophageal cancer than those without this gene defect in human high.
The next step is the key reminder: Do not remember some ten million drunk driving!
Absorption and metabolism is a dynamic and complex process, and depends on individual differences. In theory, 90% alcohol can be absorbed into the bloodstream at 0.5 to 3 hours, 90% of the absorption of alcohol in the liver metabolism. Healthy liver can break down 1 hour 13.6 grams, the initial contact with alcoholic liver disease or liver metabolism is slower.
Calculate what you can get, we can break every hour 335 ml beer (5 ), 129 Haosheng wine (13 ), 37 Haosheng liquor (45 ).
The metabolic need is a bottle of beer (600 ml) 1.8 hours, a bottle of wine (750 ml) 5.8 hours, and a bottle of white wine (500 ml) to 13.5 hours. (At this time no longer as a scientific guidance recommends ~)
Spent the night, the next day if still uncomfortable, then ......
Remember to drink plenty of water in front of the reasons have said. In addition, this time actually can drink carbonated beverages, is good. After a night, even if alcohol metabolism is not completed, has entered the blood. After the alcohol into the blood, that the blood circulation as quickly distributed in the body tissues, since fat-soluble, easily through the blood-brain barrier. The rate of ethanol into the brain depends on blood alcohol concentration, the higher the concentration of alcohol into the brain will be more, until both substantially flat. Carbon dioxide gas and ethanol, is by diffusion through, although not affect the rate of alcohol into the blood-brain barrier blood-brain barrier, but through the dilution of slowing this process.
Drinking carbonated beverages, can eat a little more "hard goods." Select some carbohydrates and high protein low fat foods, can promote metabolism, get rid of the alcohol from the blood.
Satiate, then sleep it. Many people think that drunk people sleep after a row is, in fact, people do not sleep well hangover: Alcohol can prevent the brain from the body into a deep sleep (REM), so the alcohol content in the body fall to sleep in later a nap, it has become one of the best beat a hangover.
Tips: do not drink the medicine
There is a chronic alcoholism and alcohol toxic psychosis drug treatment - disulfiram (disulfiram). Which is disulfiram generic drugs, also known as Antabuse, disulfiram wake up, have been used in many countries as a pharmaceutical alcohol. Drinking would be a serious reactions, nausea, vomiting, fear, after application of the drug, leaving the fear of drinking alcoholics, and thus play a role in alcohol. Certain drugs used clinically at present, its chemical structure or mechanism of action is similar with disulfiram can produce disulfiram-like reaction. Can cause disulfiram-like reaction of common drugs:
(1) cephalosporins such as cefoperazone, cefpiramide, cefoperazone sulbactam, cephalosporins Meng more Latamoxef, cefmetazole, cefminox, Cefmenoxime, cephalosporins Indonesia, cefotiam , cefotaxime, ceftazidime, cefsulodin ceftizoxime, cefazolin cefixime like.
(2) imidazole nitrate such as metronidazole, tinidazole, either oral or intravenous administration, no matter what kind of wine, and regardless of how much alcohol consumption will react directly with the alcohol absorbed into the bloodstream, and a double disulfiram-like symptoms. To use metronidazole after drinking, alcohol must 5d, in the use of metronidazole should also remind patients should temperance 7d or more, so as not to cause disulfiram-like reaction. The chemical structure of these drugs containing methylthio tetrazole group.
(3) other drugs and foods, such as furans furazolidone (furazolidone), chloramphenicol, ketoconazole, griseofulvin, sulfonylurea drugs such as chlorpropamide, gliclazide, tolbutamide urea (D860), glibenclamide, phenethyl quack, warfarin, trifluoperazine, Tolazoline, insulin and the like.
Finally advise everyone, or drink less wine is wonderful, the best drink. Drinking less, the more cardiovascular health.
references
The effect of fructose on the the metabolism of ethyl alcohol in man.THORNE M. ROBERT C. J Pharmacology and Experimental . July 1937 vol 60 no 3 286-295.
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