Obesity has become a global problem, "Lancet" (Lancet) magazine latest study shows that there are now nearly 30% of the world's population are obese or overweight, totaling 2.1 billion people. After the impact of obesity in addition to appearance, but also induce heart disease, stroke, diabetes, arthritis and cancer and many other diseases.
Scientists in terms of weight loss a lot of research, but it has been difficult to find a healthy balance at the same time, effective, and no pain medication or therapy. A recent study in Italy made a breakthrough, which start from the perspective of the gene, so that the above-mentioned weight loss methods possible.
[Genomic guidance recipes, easy weight loss]
The study led by Dr. principal investigator at the University of Trieste, Italy Nicola Pirastu. Dr. Nicola Pirastu convened two groups of obese volunteers, a group of 87 people as the experimental group, a group of 104 people as a control group. Start of the study, two groups of volunteers, age, sex, BMI (body mass index) is basically the same, there was no significant difference.
The researchers then analyzed the gene in the experimental group composed of volunteers, according to the known 19 genes associated with metabolism and taste, adjusting their diet. For example, a genetic map of volunteers showed that the efficiency of its relatively low fat body treatment, the researchers let their fat intake less, but the total number of calories remain unchanged. The control group of normal diet, do not make changes in accordance with the gene.
Two years later, compared with the control group, the experimental group of volunteers lost at least 33 percent of body weight, and in this group, lean body mass (body weight after subtracting the weight of body fat) ratio also increased.
Scientists conducted the study, said that this personal genome way to adjust your diet, can completely change the way to lose weight, improve people's health. "By revealing the genetic basis of taste and dietary preferences, we can not only improve the efficiency of nutritional intervention can improve the ability to follow them."
[17] food-related gene
Dr. Pirastu also carried out another study, the study of DNA samples from 4,000 volunteers in Europe and Asia were analyzed, revealed 17 genes associated with certain foods. The wide variety of food, including bacon, coffee, chicory, dark chocolate, blue cheese, ice cream, liver, butter, orange juice, yogurt, white wine and mushrooms.
Surprisingly, none of these genes has played an active role in the taste or smell.
"We found that there is a strong correlation between gene HLA-DOA and white wine preferences, but we do not know the characteristics of white wine which by this gene on." The European Society of Human Genetics annual meeting held in Milan, Dr. Pirastu presented their research results.
"Our research can help them to better understand the scientific peer environment, lifestyle, genes interact and how groups affect human health. While scientists in diet-related diseases such as obesity aspects have done a lot of work, but they are major dietary preferences into consideration - this is our work trying to solve a major problem, and we are now really just touched the surface of the problem. "
Recently, Dr. Pirastu team also found a human gene specific salt reaction.
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